When Doris Lamberson moved to Williamsburg in the mid-1970s, she was already a good friend of Thomas Graves, William & Mary's President at the time. She worked to update the President's House and is credited with adding a separate silver closet to the residence.
The Muscarelle Museum of Art became a "major focus" in her life. The museum was built because President Graves was informed by Lamberson that a Georgia O'Keefe painting hung unprotected in a campus building. Lamberson was also one of the founding members of the volunteer council for the museum. Though the museum itself if named after Joseph and Margaret Muscarelle, the building itself was named in Doris Lamberson's honor.